1 edition of Genetics of aging found in the catalog.
Genetics of aging
Includes bibliographies and index.
|Contributions||Schneider, Edward L.|
|The Physical Object|
|Pagination||xvi, 424 p. ill. ;|
|Number of Pages||424|
biology of aging Download biology of aging or read online books in PDF, EPUB, Tuebl, and Mobi Format. Click Download or Read Online button to get biology of aging book now. This site is like a library, Use search box in the widget to get ebook that you want. ISBN: X OCLC Number: Description: xv, pages: illustrations ; 24 cm. Contents: Centenarians and the genetics of longevity / Thomas Perls [and others] --Coordination of metabolic activity and stress resistance in yeast longevity / S. Michal Jazwinski --Current issues concerning the role of oxidative stress in aging / Rajindar S. Sohal, Robin J. Mockett and.
Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. He is the author of "Lifespan: Why We Age. Biology of Aging presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores the mechanisms underlying Price: $
Great inroads into the understanding of aging have been made using C. elegans as a model system. Several genes have been identified that, when mutated, can extend lifespan. Yet, much about aging remains a mystery, and new technologies that allow the simultaneous assay of expression levels of thousands of genes have been applied to the question of how and why aging might occur. Aging is a normal process linked to specific patterns and changes in the epigenome, particularly DNA sing epigenetic mechanisms and understanding the epigenetic clock might enable us to slow or reduce human aging in the future, especially as scientific research reveals new associations and insights.. After DNA methylation patterns have been established during .
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The Genetics of Aging is divided into several sections in an attempt to provide a logical progression from the level of the genome to the realm of human genetics. The relationship between the genetic material and aging will be thoroughly explored in the initial chapters.
These chapters discuss in depth the various theories that have been 5/5(1). The Molecular Genetics of Aging (Results and Problems in Cell Differentiation Book 29) - Kindle edition by Hekimi, Siegfried. Download it once and read it on your Kindle device, PC, phones or tablets.
Use features like bookmarks, note taking and highlighting while reading The Molecular Genetics of Aging (Results and Problems in Cell Differentiation Book 29).3/5(1).
About this book. Introduction. The Genetics of Genetics of aging book is divided into several sections in an attempt to provide a logical progression from the level of the genome to the realm of human genetics. The relationship between the genetic material and aging will be thoroughly explored in the initial chapters.
These chapters discuss in depth the various. Scope Probing the genetic and molecular bases of aging and aging-related processes in humans and in animal models, Genetics of Aging is a multidisciplinary section publishing research on age-related changes in gene Genetics of aging book, signaling, cell proliferation, cell death, stress responses, and senescence; the genes implicated in age-related diseases and impairment; and the role of stem cells in.
The Genetics of Aging is divided into several sections in an attempt to provide a logical progression from the level of the genome to the realm of human genetics. The relationship between the genetic material and aging will be thoroughly explored in the initial chapters. These chapters discuss in.
This book offers insight into the current state of investigation into the genetic basis of aging and longevity. It has been written by scientists at the forefront of their field, thus providing a cross-section of current research. The topics covered include work with model organisms such as yeast, fruit flies, the nematode C.
elegans, and mice. Aging is influenced by many intrinsic and extrinsic factors including genetic background, epigenetics, diet, and environment. Our ability to develop a complete model of the aging process and accurately predict outcomes designed to extend lifespan or treat age-associated pathology requires identification of the range of factors capable of influence aging and an understanding of how these.
David A. Sinclair, Ph.D., A.O. is a Professor in the Department of Genetics and co-Director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School.
He is best known for his work on understanding why we age and how to slow its effects. He obtained his Ph.D. in Molecular Genetics at the University of New South Wales, Sydney in This book focuses on the genetics of aging, which involves several physiological, psychological and social processes.
It adopts the perspective of geroscience, seeking to understand the genetic, molecular and cellular mechanisms that make aging a factor in diseases and conditions of older people.
Genetics of aging is generally concerned with life extension associated with genetic alterations, rather than with accelerated aging diseases leading to reduction in lifespan. The first mutation found to increase longevity in an animal was the age-1 gene in Caenorhabditis l Klass discovered that lifespan of C.
elegans could be altered by mutations, but Klass believed that the. Handbook of the Biology of Aging, Seventh Edition, reviews and synthesizes recent findings and discoveries in the field.
This volume is part of The Handbooks of Aging series, which also includes The Handbook of the Psychology of Aging and The Handbook of Aging and the Social Sciences. The book is organized into two parts. • Aging is controlled by genes • Mutations can accelerate or delay aging • Pathways that control aging are conserved across 1 billion years of evolution • Drugs that target these pathways may someday be used to treat diseases of aging and extend life.
Thank you!. Biology of Aging, Second Edition presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease.
Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores Reviews: 4.
The National Institute on Aging offers a video about the Baltimore Longitudinal Study of Aging. The SardiNIA Project has several pages describing research investigating longevity genes among Italians living on the Mediterranean island of Sardinia.
Human Ageing Genomic Resources offers an overview of the biology and genetics of aging. While this book focuses on the specifics of genetics and genomics, it also adopts a clinical perspective of geroscience, which seeks to understand the genetic, molecular and cellular mechanisms that make aging an important risk factor and, sometimes, a determining factor in the diseases and common chronic conditions of older people.
The book consists of 1) a history of aging and longevity related science, 2) a a handwavey survey of some interesting metabolic pathways and genetic/epigenetic programming techniques that Prof.
Sinclair and friends have pursued, 3.) philosophical, aesthetic, and moral arguments on why pursuing lifespan extension is good/5(). The maximum life span of multicellular organisms varies greatly: for a fruitfly it is about 30 days, for a dog about 20 years, and for a human about years The basic cause of aging in these organisms (eukaryotes) lies at the level of genes.
This book reviews the biology of the gene in relation to by: ISBN: OCLC Number: Description: xvi, pages: illustrations ; 24 cm: Contents: Part I. Genome level Molecular genetics of aging / Harvey V.
Samis Cytogenetics of aging / Edward L. Schneider Aging and DNA-repair capability / Raymond R. Tice Somatic mutations and aging / G.P Hirsch --Part sm level Garigan, D. et al. Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation.
Genetics– (). Aging, healthy aging, and longevity. The phenotypes used in studies of the genetics of human aging are usually lifespan (age at death), longevity (long life, usually defined as being a specific advanced age or older at the time of study), exceptional longevity (defined as attaining or exceeding a specific exceptional age), or healthy aging (a combination of old age and health, often defined as.
Robert Arking's Biology of Aging, 3rd edition, is an introductory text to the biology of aging which gives advanced undergraduate and graduate students a thorough review of the entire prior two editions have also served admirably as a reference text for clinicians and scientists.
This new edition captures the extraordinary recent advances in our knowledge of the ultimate and Reviews: Dr. Vaiserman is also a member of the editorial boards of the journals Biogerontology, Frontiers in Genetics of Aging, and Gerontology & Geriatric Research.
To-date, he has published four book chapters, as well as 65 papers in peer reviewed journals. This Scientist Believes Aging Is Optional In his new book, 'Lifespan,' celebrated scientist David Sinclair lays out exactly why we age—and why he thinks we don't have to All of the genetic.